Medical Evidence Blog

This is discussion forum for physicians, researchers, and other healthcare professionals interested in the epistemology of medical knowledge, the limitations of the evidence, how clinical trials evidence is generated, disseminated, and incorporated into clinical practice, how the evidence should optimally be incorporated into practice, and what the value of the evidence is to science, individual patients, and society.

Showing posts with label causal pathway. Show all posts
Showing posts with label causal pathway. Show all posts
Saturday, October 12, 2013

Goldilocks Meets Walter White in the ICU: Finding the Temperature (for Sepsis and Meningitis) that's Just Right

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In the Point / Counterpoint  section of the October issue of Chest, two pairs of authors spar over whether fever should be controlled in s...
Sunday, March 24, 2013

Why Most Clinical Trials Fail: The Case of Eritoran and Immunomodulatory Therapies for Sepsis

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The experimenter's view of the trees. The ACCESS trial of eritoran in the March 20, 2013 issue of JAMA can serve as a springboar...
Tuesday, March 12, 2013

Falling to Pieces: Hemolysis of the Hemoglobin Hypothesis

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A paramount goal of this blog is to understand the evidence as it applies to the epistemology of medical knowledge, hypothesis testing,...
4 comments:
Tuesday, December 4, 2012

The Cholesterol Hypothesis on the Beam: Dalcetrapib, PCSK9 inhibitors, and "off-target" effects of statins

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The last month has witnessed the publication of three lines of research that could tip the balance of the evidence for the cholesterol ...
4 comments:
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Scott K. Aberegg, M.D., M.P.H.
Professor of Medicine, University of Utah. Former affiliations: Outside Hospital x 7.5 years; Assistant Professor, The Ohio State University; Fellowship & MPH: Johns Hopkins Hospital & Bloomberg School of Public Health, Baltimore, MD; Residency: The University of New Mexico Health Sciences Center; MD: The Ohio State University; BA, Spanish: Miami University, Ohio. All views are my own with NO institutional endorsement.
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