Medical Evidence Blog

This is discussion forum for physicians, researchers, and other healthcare professionals interested in the epistemology of medical knowledge, the limitations of the evidence, how clinical trials evidence is generated, disseminated, and incorporated into clinical practice, how the evidence should optimally be incorporated into practice, and what the value of the evidence is to science, individual patients, and society.

Showing posts with label type I error. Show all posts
Showing posts with label type I error. Show all posts
Sunday, April 21, 2019

A Finding of Noninferiority Does Not Show Efficacy - It Shows Noninferiority (of short course rifampin for MDR-TB)

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An image of two separated curves from Mayo's book SIST Published in the March 28th, 2019 issue of the NEJM is the STREAM trial of a...
Tuesday, April 4, 2017

Tipping the Scales of Noninferiority: Abbott's "Emboshield and Xact Carotid Stent System"

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I just stumbled across this and think it's worth musing over it a bit.  The recently published ACT I trial by Rosenfield et al  is a ...
Wednesday, July 22, 2015

There is (No) Evidence For That: Epistemic Problems in Evidence Based Medicine

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Below is a Power Point Presentation that I have delivered several times recently including one iteration at the SMACC conference in Chicag...
2 comments:
Sunday, April 6, 2014

Underperforming the Market: Why Researchers are Worse than Professional Stock Pickers and A Way Out

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I was reading in the NYT yesterday a story about Warren Buffet and how the Oracle of Omaha has trailed the S&P 500 for four of the l...
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Scott K. Aberegg, M.D., M.P.H.
Professor of Medicine, University of Utah. Former affiliations: Outside Hospital x 7.5 years; Assistant Professor, The Ohio State University; Fellowship & MPH: Johns Hopkins Hospital & Bloomberg School of Public Health, Baltimore, MD; Residency: The University of New Mexico Health Sciences Center; MD: The Ohio State University; BA, Spanish: Miami University, Ohio. All views are my own with NO institutional endorsement.
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